Background: Cirrhosis is a progressive liver disease with high mortality and frequent complications, notably acute kidney injury (AKI), which occurs in up to 50% of hospitalized patients and worsens outcomes. AKI stems from complex hemodynamic, inflammatory, and metabolic changes, making early detection essential. Many predictive tools lack accuracy, interpretability, and alignment with intensive care unit (ICU) workflows. This study developed an interpretable machine learning model for early AKI prediction in critically ill patients with cirrhosis. Methods: We conducted a retrospective analysis of the MIMIC-IV v2.2 database, identifying 1240 adult ICU patients with cirrhosis and excluding those with ICU stays under 48 hours or missing key data. Laboratory and physiological variables from the first 48 hours were extracted. The pipeline included preprocessing, missingness filtering, LASSO feature selection, and SMOTE class balancing. Six algorithms-LightGBM, CatBoost, XGBoost, logistic regression, naive Bayes, and neural networks-were trained and evaluated using AUROC, accuracy, F1-score, sensitivity, specificity, and predictive values. Results: LightGBM achieved the best performance (AUROC 0.808, 95% CI 0.741-0.856; accuracy 0.704; NPV 0.911). Key predictors included prolonged partial thromboplastin time, absence of outside-facility 20G placement, low pH, and altered pO2, consistent with known cirrhosis-AKI mechanisms and suggesting actionable targets. Conclusion: The LightGBM-based model enables accurate early AKI risk stratification in ICU patients with cirrhosis using routine clinical variables. Its high negative predictive value supports safe de-escalation for low-risk patients, and interpretability fosters clinician trust and targeted prevention. External validation and integration into electronic health record systems are warranted.

This study presents a comprehensive bibliometric and topic analysis of the disaster informatics literature published between January 2020 to September 2022. Leveraging a large-scale corpus and advanced techniques such as pre-trained language models and generative AI, we identify the most active countries, institutions, authors, collaboration networks, emergent topics, patterns among the most significant topics, and shifts in research priorities spurred by the COVID-19 pandemic. Our findings highlight (1) countries that were most impacted by the COVID-19 pandemic were also among the most active, with each country having specific research interests, (2) countries and institutions within the same region or share a common language tend to collaborate, (3) top active authors tend to form close partnerships with one or two key partners, (4) authors typically specialized in one or two specific topics, while institutions had more diverse interests across several topics, and (5) the COVID-19 pandemic has influenced research priorities in disaster informatics, placing greater emphasis on public health. We further demonstrate that the field is converging on multidimensional resilience strategies and cross-sectoral data-sharing collaborations or projects, reflecting a heightened awareness of global vulnerability and interdependency. Collecting and quality assurance strategies, data analytic practices, LLM-based topic extraction and summarization approaches, and result visualization tools can be applied to comparable datasets or solve similar analytic problems. By mapping out the trends in disaster informatics, our analysis offers strategic insights for policymakers, practitioners, and scholars aiming to enhance disaster informatics capacities in an increasingly uncertain and complex risk landscape.

Conversational Information Retrieval (CIR) systems, while offering intuitive access to information, face a significant challenge: reliably handling unanswerable questions to prevent the generation of misleading or hallucinated content. Traditional approaches often rely on external classifiers, which can introduce inconsistencies with the core generative Large Language Models (LLMs). This paper introduces Self-Aware LLM for Unanswerability (SALU), a novel approach that deeply integrates unanswerability detection directly within the LLM's generative process. SALU is trained using a multi-task learning framework for both standard Question Answering (QA) and explicit abstention generation for unanswerable queries. Crucially, it incorporates a confidence-score-guided reinforcement learning with human feedback (RLHF) phase, which explicitly penalizes hallucinated responses and rewards appropriate abstentions, fostering intrinsic self-awareness of knowledge boundaries. Through extensive experiments on our custom-built C-IR_Answerability dataset, SALU consistently outperforms strong baselines, including hybrid LLM-classifier systems, in overall accuracy for correctly answering or abstaining from questions. Human evaluation further confirms SALU's superior reliability, achieving high scores in factuality, appropriate abstention, and, most importantly, a dramatic reduction in hallucination, demonstrating its ability to robustly "know when to say 'I don't know'."

Radiomics-based AI models show promise for breast cancer diagnosis but often lack interpretability, limiting clinical adoption. This study addresses the gap between radiomic features (RF) and the standardized BI-RADS lexicon by proposing a dual-dictionary framework. First, a Clinically-Informed Feature Interpretation Dictionary (CIFID) was created by mapping 56 RFs to BI-RADS descriptors (shape, margin, internal enhancement) through literature and expert review. The framework was applied to classify triple-negative breast cancer (TNBC) versus non-TNBC using dynamic contrast-enhanced MRI from a multi-institutional cohort of 1,549 patients. We trained 27 machine learning classifiers with 27 feature selection methods. SHapley Additive exPlanations (SHAP) were used to interpret predictions and generate a complementary Data-Driven Feature Interpretation Dictionary (DDFID) for 52 additional RFs. The best model, combining Variance Inflation Factor (VIF) selection with Extra Trees Classifier, achieved an average cross-validation accuracy of 0.83. Key predictive RFs aligned with clinical knowledge: higher Sphericity (round/oval shape) and lower Busyness (more homogeneous enhancement) were associated with TNBC. The framework confirmed known imaging biomarkers and uncovered novel, interpretable associations. This dual-dictionary approach (BM1.0) enhances AI model transparency and supports the integration of RFs into routine breast cancer diagnosis and personalized care.

Motion capture (MoCap) data from wearable Inertial Measurement Units (IMUs) is vital for applications in sports science, but its utility is often compromised by missing data. Despite numerous imputation techniques, a systematic performance evaluation for IMU-derived MoCap time-series data is lacking. We address this gap by conducting a comprehensive comparative analysis of statistical, machine learning, and deep learning imputation methods. Our evaluation considers three distinct contexts: univariate time-series, multivariate across subjects, and multivariate across kinematic angles. To facilitate this benchmark, we introduce the first publicly available MoCap dataset designed specifically for imputation, featuring data from 53 karate practitioners. We simulate three controlled missingness mechanisms: missing completely at random (MCAR), block missingness, and a novel value-dependent pattern at signal transition points. Our experiments, conducted on 39 kinematic variables across all subjects, reveal that multivariate imputation frameworks consistently outperform univariate approaches, particularly for complex missingness. For instance, multivariate methods achieve up to a 50% mean absolute error reduction (MAE from 10.8 to 5.8) compared to univariate techniques for transition point missingness. Advanced models like Generative Adversarial Imputation Networks (GAIN) and Iterative Imputers demonstrate the highest accuracy in these challenging scenarios. This work provides a critical baseline for future research and offers practical recommendations for improving the integrity and robustness of Mo-Cap data analysis.

This Paper discusses the growing popularity of online medical diagnosis as an alternative to traditional doctor visits. It highlights the limitations of existing tools and emphasizes the advantages of using ChatGPT, which provides real-time, personalized medical diagnosis at no cost. The paragraph summarizes a research study that evaluated the performance of ChatGPT in Arabic medical diagnosis. The study involved compiling a dataset of disease information and generating multiple messages for each disease using different prompting techniques. ChatGPT's performance was assessed by measuring the similarity between its responses and the actual diseases. The results showed promising performance, with average scores of around 76% for similarity measures. Various prompting techniques were used, and chain prompting demonstrated a relative advantage. The study also recorded an average response time of 6.12 seconds for the ChatGPT API, which is considered acceptable but has room for improvement. While ChatGPT cannot replace human doctors entirely, the findings suggest its potential in emergency cases and addressing general medical inquiries. Overall, the study highlights ChatGPT's viability as a valuable tool in the medical field.

neumonia is a life-threatening lung infection resulting from several different viral infections. Identifying and treating pneumonia on chest X-ray images can be difficult due to its similarity to other pulmonary diseases. Thus, the existing methods for predicting pneumonia cannot attain substantial levels of accuracy. Therefore, this paper presents a computer-aided classification of pneumonia, coined as Ensemble Learning (EL), to simplify the diagnosis process on chest X-ray images. Our proposal is based on Convolutional Neural Network (CNN) models, which are pre-trained CNN models that have been recently employed to enhance the performance of many medical tasks instead of training CNN models from scratch. We propose to use three well-known CNN pre-trained (DenseNet169, MobileNetV2 and Vision Transformer) using the ImageNet database. Then, these models are trained on the chest X-ray data set using fine-tuning. Finally, the results are obtained by combining the extracted features from these three models during the experimental phase. The proposed EL approach outperforms other existing state-of-the-art methods, and it obtains an accuracy of 93.91% and a F1-Score of 93.88% on the testing phase. Identifying and treating pneumonia on chest X-ray images can be difficult due to its similarity to other pulmonary diseases. Thus, the existing methods for predicting pneumonia cannot attain substantial levels of accuracy. Therefore, this paper presents a computer-aided classification of pneumonia, coined as Ensemble Learning (EL), to simplify the diagnosis process on chest X-ray images. Our proposal is based on Convolutional Neural Network (CNN) models, which are pretrained CNN models that have been recently employed to enhance the performance of many medical tasks instead of training CNN models from scratch.

Federated learning is a very convenient approach for scenarios where (i) the exchange of data implies privacy concerns and/or (ii) a quick reaction is needed. In smart healthcare systems, both aspects are usually required. In this paper, we work on the first scenario, where preserving privacy is key and, consequently, building a unique and massive medical image data set by fusing different data sets from different medical institutions or research centers (computation nodes) is not an option. We propose an ensemble federated learning (EFL) approach that is based on the following characteristics: First, each computation node works with a different data set (but of the same type). They work locally and apply an ensemble approach combining eight well-known CNN models (densenet169, mobilenetv2, xception, inceptionv3, vgg16, resnet50, densenet121, and resnet152v2) on Chest X-ray images. Second, the best two local models are used to create a local ensemble model that is shared with a central node. Third, the ensemble models are aggregated to obtain a global model, which is shared with the computation nodes to continue with a new iteration. This procedure continues until there are no changes in the best local models. We have performed different experiments to compare our approach with centralized ones (with or without an ensemble approach)\color{black}. The results conclude that our proposal outperforms these ones in Chest X-ray images (achieving an accuracy of 96.63\%) and offers very competitive results compared to other proposals in the literature.

The Internet of Medical Things (IoMT) has dramatically benefited medical professionals that patients and physicians can access from all regions. Although the automatic detection and prediction of diseases such as melanoma and leukemia is still being researched and studied in IoMT, existing approaches are not able to achieve a high degree of efficiency. Thus, with a new approach that provides better results, patients would access the adequate treatments earlier and the death rate would be reduced. Therefore, this paper introduces an IoMT proposal for medical images classification that may be used anywhere, i.e. it is an ubiquitous approach. It was design in two stages: first, we employ a Transfer Learning (TL)-based method for feature extraction, which is carried out using MobileNetV3; second, we use the Chaos Game Optimization (CGO) for feature selection, with the aim of excluding unnecessary features and improving the performance, which is key in IoMT. Our methodology was evaluated using ISIC-2016, PH2, and Blood-Cell datasets. The experimental results indicated that the proposed approach obtained an accuracy of 88.39% on ISIC-2016, 97.52% on PH2, and 88.79% on Blood-cell. Moreover, our approach had successful performances for the metrics employed compared to other existing methods.

Machine learning (ML) has emerged as a prominent field of research in computer science and other related fields, thereby driving advancements in other domains of interest. As the field continues to evolve, it is crucial to understand the landscape of highly cited publications to identify key trends, influential authors, and significant contributions made thus far. In this paper, we present a comprehensive bibliometric analysis of highly cited ML publications. We collected a dataset consisting of the top-cited papers from reputable ML conferences and journals, covering a period of several years from 1959 to 2022. We employed various bibliometric techniques to analyze the data, including citation analysis, co-authorship analysis, keyword analysis, and publication trends. Our findings reveal the most influential papers, highly cited authors, and collaborative networks within the machine learning community. We identify popular research themes and uncover emerging topics that have recently gained significant attention. Furthermore, we examine the geographical distribution of highly cited publications, highlighting the dominance of certain countries in ML research. By shedding light on the landscape of highly cited ML publications, our study provides valuable insights for researchers, policymakers, and practitioners seeking to understand the key developments and trends in this rapidly evolving field.